Recombinant Mouse CD112/Nectin-2 Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSM041226-10ug | 10ug | £126.00 |
Quantity:
| PKSM041226-50ug | 50ug | £219.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
CD112;Nectin-2
Accession:
NP_033016.3
Activity:
Immobilized Human DNAM-1-Fc(Cat: PKSH033729) at 2ug/ml(100 ul/well) can bind Human Nectin-2-His.
Background:
Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.
Calculated MW:
35.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
40-45 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln32-Gly351
Target Synonym:
CD112;nectin2;Herpes virus entry mediator B;Herpesvirus entry mediator B;HveB;Murine herpes virus entry protein B;mHveB;Poliovirus receptor homolog;Poliovirus receptor-related protein 2;Pvrl2;