Recombinant Mouse 4-1BB/TNFRSF9 Protein (aa 24-187, Fc Tag)(Active)
| Code | Size | Price |
|---|
| PKSM041199-10ug | 10ug | £283.00 |
Quantity:
| PKSM041199-50ug | 50ug | £436.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
4-1BB;TNFRSF9
Accession:
NP_001070976.1
Activity:
Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.05ug/ml(100 ul/well) can bind Mouse 4-1BB-Fc.
Background:
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Calculated MW:
44.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
60-70 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Val24-Leu187
Target Synonym:
4-1BB;A930040I11Rik;AA408498;AI325004;Cd137;CDw137;ILA;Ly63;Secreted CD137 antigen;Tumor necrosis factor receptor superfamily member 9;Tnfrsf9