Recombinant Human CD30/TNFRSF8 Protein (His Tag)

Elabscience
Product Code: PKSH033727
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH033727-10ug10ug£166.00
Quantity:
PKSH033727-50ug50ug£315.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
CD30;TNFRSF8
Accession:
P28908
Background:
CD30; also known as TNFRSF8; is a cell membrane protein of the tumor necrosis factor receptor family; which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated; but not by resting; T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody?drug conjugate.
Calculated MW:
39.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Tris;150mM NaCl;pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
60-95 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Phe19-Lys379
Target Synonym:
Tumor necrosis factor receptor superfamily member 8;CD30L receptor;Ki-1 antigen;Lymphocyte activation antigen CD30;CD30;TNFRSF8;D1S166E
UNIProt ID:
P28908