Recombinant Human EphA7/EHK3 Protein (His Tag)(Active)

Elabscience
Product Code: PKSH033689
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH033689-10ug10ug£166.00
Quantity:
PKSH033689-50ug50ug£315.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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Further Information

Abbreviation:
EphA7;EHK3
Accession:
Q15375
Activity:
Immobilized Human EphA7-His at 2ug/ml(100 ul/well) can bind Human EFNA4-Fc-6His(Cat: PKSH032392). The ED50 of Human EphA7-His is 1. 5190 ug/ml.
Background:
Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.
Calculated MW:
60.19 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
72 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln28-Ile556
Target Synonym:
Ephrin Type-A Receptor 7;EPH Homology Kinase 3;EHK-3;EPH-Like Kinase 11;EK11;hEK11;EPHA7;EHK3;HEK11
UNIProt ID:
Q15375