Recombinant Human EphB1/EPHT2 Protein (aa 564-984, His Tag)(Active)
| Code | Size | Price |
|---|
| PKSH033688-10ug | 10ug | £170.00 |
Quantity:
| PKSH033688-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
EphB1;EPHT2
Accession:
P54762
Activity:
Immobilized Human EphB1-His at 10ug/ml(100 ul/well) can bind Mouse EFNB2-Fc(Cat: PKSM041012). The ED50 of Human EphB1-His is 53. 1 ug/ml.
Background:
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains; one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner; which also correlated with its association with Grb7; an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1; ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development; angiogenesis; and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
Calculated MW:
48.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Tris;150mM NaCl;pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
49 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser564-Ala984
Target Synonym:
Ephrin Type-B Receptor 1;ELK;EPH Tyrosine Kinase 2;EPH-Like Kinase 6;EK6;hEK6;Neuronally-Expressed EPH;Related Tyrosine Kinase;NET;Tyrosine-Protein Kinase Receptor EPH-2;EPHB1;ELK;EPHT2;HEK6
UNIProt ID:
P54762