Recombinant Human CD4/LEU3 Protein (Fc Tag)
| Code | Size | Price |
|---|
| PKSH033507-10ug | 10ug | £166.00 |
Quantity:
| PKSH033507-50ug | 50ug | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
CD4;LEU3
Accession:
P01730
Background:
CD4 is an approximately 55 kDa type-I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T-lymphocytes. It is a standard phenotype marker for the identification of T-cell populations. Mature human CD4 consists of a 371-amino acid extracellular region containing four immunoglobulin-like domains; a 22-aa transmembrane segment; and a 40 aa cytoplasmic domain. CD4 is expressed along with CD8 on double positive T-cells during their development in the thymus. CD4 binds directly to MHC class-II molecules on antigen presenting cells (10). This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction. CD4 also functions as a chemotactic receptor for IL-16 and; in human; as a co-receptor for the gp120 surface glycoprotein of HIV-1.
Calculated MW:
67.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS;1mM EDTA;PH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
70-85 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Lys26-Trp390
Target Synonym:
T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4;CD4mut
UNIProt ID:
P01730