Recombinant Human TPP1/CLN2 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH033493-10ug | 10ug | £256.00 |
Quantity:
| PKSH033493-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
TPP1;CLN2
Accession:
O14773
Background:
Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
Calculated MW:
60.35 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl,150mM NaCl,1mM GaCl2,10% Glycerol,pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
74 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser20-Pro563
Target Synonym:
Tripeptidyl-Peptidase 1;TPP-1;Cell Growth-Inhibiting Gene 1 Protein;Lysosomal Pepstatin-Insensitive Protease;LPIC;Tripeptidyl Aminopeptidase;TPP1;CLN2;GIG1;LPIC;SCAR7;TPP-1
UNIProt ID:
O14773