Recombinant Human HABP2 Protein (His Tag)

Elabscience
Product Code: PKSH033464
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH033464-10ug10ug£219.00
Quantity:
PKSH033464-50ug50ug£497.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Documents

Further Information

Abbreviation:
HABP2
Accession:
Q14520
Background:
Hyaluronan-binding protein 2 (HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
Calculated MW:
36.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
38 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Gln279
Target Synonym:
Hyaluronan-binding protein 2;Factor VII-activating protease;Factor seven-activating protease;Hepatocyte growth factor activator-like protein;Plasma hyaluronan-binding protein
UNIProt ID:
Q14520