Recombinant Human PLA2G7/Lp-PLA2 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH033398-10ug | 10ug | £256.00 |
Quantity:
| PKSH033398-50ug | 50ug | £553.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
PLA2G7;Lp-PLA2
Accession:
Q13093-1
Background:
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.
Calculated MW:
48.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM HAc-NaCl, 150mM NaCl, 10% Glycerol, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
54 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Phe22-Asn441
Target Synonym:
2-acetyl-1-alkylglycerophosphocholine esterase;EC 3.1.1;EC 3.1.1.47;1-alkyl-2-acetylglycerophosphocholine esterase;Group-VIIA phospholipase A2;gVIIA-PLA2;LDL-associated phospholipase A2;LDL-PLA(2);LDL-PLA2;lipoprotein-associated phospholipase A2;LpPLA2;Lp-PLA2;PAF acetylhydrolase;PAF-AH;PAFAHPAF 2-acylhydrolase;phospholipase A2;group VII (platelet-activating factor acetylhydrolase;PLA2G7;plasma);platelet-activating factor acetylhydrolase
UNIProt ID:
Q13093