Recombinant Human IL-22BP/IL-22RA2 Protein (His Tag)(Active)
| Code | Size | Price |
|---|
| PKSH033384-10ug | 10ug | £180.00 |
Quantity:
| PKSH033384-50ug | 50ug | £378.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Cell Culture
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
IL-22BP;IL-22RA2
Accession:
Q969J5-2
Activity:
Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 113.2 ng/ml in the presence of 500 ng/mL of Recombinant Human IL-22.
Background:
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Calculated MW:
25.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB;150mM NaCl;pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
44 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Thr 22-Pro231
Target Synonym:
Interleukin-22 Receptor Subunit Alpha-2;IL-22 Receptor Subunit Alpha-2;IL-22R-Alpha-2;IL-22RA2;Cytokine Receptor Class-II Member 10;Cytokine Receptor Family 2 Member 10;CRF2-10;Cytokine Receptor Family Type 2 Soluble 1;CRF2-S1;Interleukin-22-Binding Protein;IL-22BP;IL22BP;ZcytoR16;IL22RA2
UNIProt ID:
Q969J5