Recombinant Human CFHR1 Protein (His Tag)

Elabscience
Product Code: PKSH033320
Product Group: Recombinant Proteins
Supplier: Elabscience
CodeSizePrice
PKSH033320-10ug10ug£180.00
Quantity:
PKSH033320-50ug50ug£378.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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Further Information

Abbreviation:
CFHR1
Accession:
Q03591
Background:
Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H; the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains; termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five; approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation; lipid metabolism and lipoprotein complexes that bind PMNs to LPS.
Calculated MW:
36.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl;2mM EDTA, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
39-43 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Glu19-Arg330
Target Synonym:
Complement Factor H-Related Protein 1;FHR-1;H Factor-Like Protein 1;H-Factor-Like 1;H36;CFHR1;CFHL;CFHL1;CFHL1P;CFHR1P;FHR1;HFL1;HFL2
UNIProt ID:
Q03591