Recombinant Human SUMO1 Protein (His Tag)
| Code | Size | Price |
|---|
| PKSH033311-10ug | 10ug | £89.00 |
Quantity:
| PKSH033311-50ug | 50ug | £106.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
SUMO1
Accession:
AAH66306
Background:
Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Calculated MW:
13.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
17-19 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Val101
Target Synonym:
Small Ubiquitin-Related Modifier 1;SUMO-1;GAP-Modifying Protein 1;GMP1;SMT3 Homolog 3;Sentrin;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein SMT3C;Smt3C;Ubiquitin-Like Protein;UBL1;SUMO1;SMT3C;SMT3H3;UBL1;DAP1;OFC10;SENP2;SMT3