PE Anti-Mouse CD45 Antibody[30-F11]
| Code | Size | Price |
|---|
| E-AB-F1136D-50Tests | 50Tests | £99.00 |
Quantity:
| E-AB-F1136D-100Tests | 100Tests | £115.00 |
Quantity:
| E-AB-F1136D-100Testsx2 | 100Testsx2 | £143.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgG2b, κ
Antibody Clone: 30-F11
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Further Information
Abbreviation:
CD45
Background:
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PE
GeneID:
19264
Target Synonym:
Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
UNIProt ID:
P06800
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
References
- https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-22-0318/710112
- https://link.springer.com/article/10.1007/s00262-021-02894-8
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