AF/LE Purified Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]
Code | Size | Price |
---|
E-AB-F11120-50ug | 50ug | £140.00 |
Quantity:
E-AB-F11120-500ug | 500ug | £341.00 |
Quantity:
E-AB-F11120-1mg | 1mg | £475.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgM, κ
Antibody Clone: RA3.3A 1/6.1
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Cell Differentiation
- Depletion
- Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C. Do not freeze.
Further Information
Abbreviation:
CD45R/B220
Background:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Buffer:
0.2 um filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration:
0.5 mg/mL
Conjugation:
None (Purified antibody-Azide Free/Low endotoxin)
GeneID:
192,645,788
Target Synonym:
B220;
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 2.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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