APC Anti-Human CD273/PD-L2 Antibody[24F.10C12]
Code | Size | Price |
---|
E-AB-F1175E-20Tests | 20Tests | £143.00 |
Quantity:
E-AB-F1175E-100Tests | 100Tests | £251.00 |
Quantity:
E-AB-F1175E-100Testsx2 | 100Testsx2 | £338.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a, κ
Antibody Clone: 24F.10C12
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Images
Further Information
Abbreviation:
CD273/PD-L2
Background:
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
APC
GeneID:
80380
Target Synonym:
B7DC; CD273; PDCD1L2; PDL2;
UNIProt ID:
Q9BQ51
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
References
- https://www.sciencedirect.com/science/article/pii/S2211124719314159
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