APC Anti-Human CD206 Antibody[15-2]
Code | Size | Price |
---|
E-AB-F1161E-20Tests | 20Tests | £149.00 |
Quantity:
E-AB-F1161E-100Tests | 100Tests | £253.00 |
Quantity:
E-AB-F1161E-100Testsx2 | 100Testsx2 | £342.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, κ
Antibody Clone: 15-Feb
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Images
Further Information
Abbreviation:
CD206/MMR
Background:
Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
APC
GeneID:
4360
Target Synonym:
CLEC13D;CLEC13DL;MRC1L1;MMR;hMR;
UNIProt ID:
P22897
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
References
- https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01192-w
- https://www.sciencedirect.com/science/article/pii/S0141813022017585
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