ZC3H7A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64495-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64495-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64495-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ZC3H7A
Background:
The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
19kDa/110kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human ZC3H7A (NP_054872.2).
ObservedMW:
120kDa
Purification method:
Affinity purification
Target Synonym:
ZC3H7A;HSPC055;ZC3H7;ZC3HDC7
UNIProt ID:
Q8IWR0