XRCC5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64590-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64590-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64590-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
XRCC5
Background:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human XRCC5 (NP_066964.1).
Purification method:
Affinity purification
Target Synonym:
XRCC5;KARP-1;KARP1;KU80;KUB2;Ku86;NFIV
UNIProt ID:
P13010
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8139207/