Vimentin Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70081-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70081-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70081-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Vimentin
Background:
Vimentin,also named as VIM,belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells,especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092),suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
57kDa
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse vimentin
ObservedMW:
57kDa
Purification method:
Affinity purification
Target Synonym:
CTRCT30;Epididymis luminal protein 113;FLJ36605;HEL113;VIM;VIME;Vimentin
UNIProt ID:
P08670,P20152,P31000
References
- https://www.mdpi.com/2055064
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/
- https://www.hindawi.com/journals/cjgh/2022/5332129/