UNC13D Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64476-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64476-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64476-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
UNC13D
Background:
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
41kDa/123kDa/128kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant fusion protein of human UNC13D (NP_954712.1).
ObservedMW:
123kDa
Purification method:
Affinity purification
Target Synonym:
UNC13D;FHL3;HLH3;HPLH3;Munc13-4
UNIProt ID:
Q70J99