TRIM5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65386-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65386-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65386-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TRIM5
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
29kDa/31kDa/37kDa/40kDa/46kDa/56kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human TRIM5 (NP_149083.2).
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
TRIM5;RNF88;TRIM5alpha
UNIProt ID:
Q9C035