TPP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61031-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61031-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61031-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TPP1
Background:
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
34kDa/61kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human TPP1 (NP_000382.3).
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
TPP1;CLN2;GIG1;LPIC;SCAR7;TPP-1
UNIProt ID:
O14773