SOCS3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-63265-60uL | 60uL | £210.00 |
Quantity:
| E-AB-63265-120uL | 120uL | £291.00 |
Quantity:
| E-AB-63265-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SOCS3
Background:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
24kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human SOCS3 (NP_003946.3).
ObservedMW:
33kDa
Purification method:
Affinity purification
Target Synonym:
SOCS3;ATOD4;CIS3;Cish3;SOCS-3;SSI-3;SSI3
UNIProt ID:
O14543
References
- https://www.mdpi.com/1863624