SOCS1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70245-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70245-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70245-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SOCS1
Background:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
0.89 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse SOCS1
Purification method:
Affinity purification
Target Synonym:
CISH 1;CISH1;Cytokine inducible SH2 protein 1;JAB;JAK binding protein;JAK-binding protein;Janus kinase binding protein;SOCS 1;SOCS-1;Socs1;SOCS1;SSI 1;SSI-1;SSI1;STAT induced STAT inhibitor 1;STAT-induced STAT inhibitor 1;Suppressor of cytokine signaling 1;Supressor of cytokine signalling 1;TEC interacting protein 3;Tec-interacting protein 3;TIP 3;TIP-3;TIP3
UNIProt ID:
O35716,Q9QX78