SNCA Polyclonal Antibody

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Elabscience
Product Code: E-AB-70302
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-70302-60uL60uL£184.00
Quantity:
E-AB-70302-120uL120uL£251.00
Quantity:
E-AB-70302-200uL200uL£351.00
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Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of various samples using SNCA Polyclonal Antibody at dilution of 1:600.
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Western Blot analysis of various samples using SNCA Polyclonal Antibody at dilution of 1:600.

Documents

Further Information

Abbreviation:
SNCA
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
14kDa
Concentration:
0.92 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse α-synuclein
ObservedMW:
15-19kDa
Purification method:
Affinity purification
Target Synonym:
Alpha synuclein;Alpha-synuclein;Alpha-synuclein;isoform NACP140;alphaSYN;MGC105443;MGC110988;MGC127560;MGC64356;NACP;Non A beta component of AD amyloid;Non A4 component of amyloid;Non A4 component of amyloid precursor;Non-A beta component of AD amyloid;Non-A-beta component of alzheimers disease amyloid;precursor of;Non-A4 component of amyloid precursor;Non-A4 component of amyloid;precursor of;OTTHUMP00000218549;OTTHUMP00000218551;OTTHUMP00000218552;OTTHUMP00000218553;OTTHUMP00000218554;PARK 1;PARK 4;PARK1;PARK4;Parkinson disease (autosomal dominant;Lewy body) 4;Parkinson disease familial 1;SNCA;Snca synuclein;alpha (non A4 component of amyloid precursor);SYN;Synuclein alpha;Synuclein alpha 140;Synuclein;alpha (non A4 component of amyloid precursor);SYUA
UNIProt ID:
P37840,O55042,P37377

References

  • https://link.springer.com/article/10.1007/s00204-022-03414-y