SLC6A4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64947-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64947-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64947-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SLC6A4
Background:
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
70kDa/74kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human SLC6A4 (NP_001036.1).
ObservedMW:
75KDa
Purification method:
Affinity purification
Target Synonym:
5-HTT;5-HTTLPR;5HTT;HTT;OCD1;SERT;SERT1;hSERT;SLC6A4
UNIProt ID:
P31645