SIM2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65198-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65198-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65198-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SIM2
Background:
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
63kDa/73kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SIM2 (NP_033664.2).
ObservedMW:
56kDa
Purification method:
Affinity purification
Target Synonym:
SIM2;HMC13F06;HMC29C01;SIM;bHLHe15
UNIProt ID:
Q14190