SESN3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-63213-60uL | 60uL | £210.00 |
Quantity:
| E-AB-63213-120uL | 120uL | £291.00 |
Quantity:
| E-AB-63213-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SESN3
Background:
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
36kDa/41kDa/57kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000
Immunogen:
Recombinant fusion protein of human SESN3 (NP_653266.2).
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
SESN3;SEST3;sestrin-3
UNIProt ID:
P58005