SEMA3C Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65295-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65295-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65295-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SEMA3C
Background:
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
26kDa/85kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human SEMA3C (NP_006370.1).
ObservedMW:
85kDa
Purification method:
Affinity purification
Target Synonym:
SEMA3C;SEMAE;SemE
UNIProt ID:
Q99985