S100B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70296-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70296-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70296-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
S100B
Background:
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
0.54 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse S100B
Purification method:
Affinity purification
Target Synonym:
NEF;Protein S100 B;Protein S100-B;S 100 calcium binding protein beta chain;S 100 protein beta chain;S-100 protein beta chain;S-100 protein subunit beta;S100;S100 calcium binding protein beta (neural);S100 calcium-binding protein B;S100 protein beta chain;S100B;S100B;S100beta
UNIProt ID:
P50114,P04631