S100A4 Polyclonal Antibody

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Elabscience
Product Code: E-AB-70283
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-70283-60uL60uL£184.00
Quantity:
E-AB-70283-120uL120uL£251.00
Quantity:
E-AB-70283-200uL200uL£351.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry analysis of paraffin-embedded human lung cancer using S100A4 Polyclonal Antibody at dilution of 1:400.
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using S100A4 Polyclonal Antibody at dilution of 1:400.

Documents

Further Information

Abbreviation:
S100A4
Background:
S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
12kDa
Concentration:
0.75 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:300-1:800
Immunogen:
Recombinant protein corresponding to Mouse S100A4
ObservedMW:
12kDa
Purification method:
Affinity purification
Target Synonym:
18A2;42A;calcium Placental protein;Calvasculin;CAPL;Fibroblast specific protein 1 (FSP1);Fibroblast specific protein 1;Fibroblast specific protein;FSP1;Leukemia multidrug resistance associated protein;Malignant transformation suppression 1 (MTS1);Malignant transformation suppression 1;Metastasin;MTS1;OTTHUMP00000015467;OTTHUMP00000015468;P9KA;PEL98;Placental calcium-binding protein;Protein Mts1;Protein S100 A4;Protein S100-A4;S100 calcium binding protein A4 (calcium protein;calvasculin;metastasin;murine placental homolog);S100 calcium binding protein A4;S100 calcium-binding protein A4;S100a4;S10A4
UNIProt ID:
P26447,P07091,P05942