RUNX1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-60579-60uL | 60uL | £210.00 |
Quantity:
E-AB-60579-120uL | 120uL | £291.00 |
Quantity:
E-AB-60579-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
RUNX1
Background:
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100 IF 1:50-1:200
Immunogen:
A synthetic peptide of human RUNX1 (NP_001745.2).
Purification method:
Affinity purification
Target Synonym:
RUNX1;AML1;AML1-EVI-1;AMLCR1;CBF2alpha;CBFA2;EVI-1;PEBP2aB;PEBP2alpha
UNIProt ID:
Q01196