RNF7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61633-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61633-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61633-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RNF7
Background:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:20-1:50
Immunogen:
Recombinant fusion protein of human RNF7 (NP_055060.1).
Purification method:
Affinity purification
Target Synonym:
RNF7;CKBBP1;ROC2;SAG
UNIProt ID:
Q9UBF6