RASSF1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60249-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60249-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60249-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RASSF1
Background:
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
8kDa/9kDa/16kDa/21kDa/31kDa/38kDa/39kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human RASSF1
ObservedMW:
39kDa
Purification method:
Affinity purification
Target Synonym:
RASSF1;123F2;NORE2A;RASSF1A;RDA32;REH3P21
UNIProt ID:
Q9NS23