RAP1A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60120-60uL | 60uL | £224.00 |
Quantity:
| E-AB-60120-120uL | 120uL | £317.00 |
Quantity:
| E-AB-60120-200uL | 200uL | £465.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RAP1A
Background:
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
A synthetic peptide of human RAP1A (NP_002875.1).
Purification method:
Affinity purification
Target Synonym:
RAP1A;C21KG;G-22K;KREV-1;KREV1;RAP1;SMGP21
UNIProt ID:
P62834