RAC2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40245-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40245-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40245-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40245-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RAC2
Background:
RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien
Purification method:
Affinity purification
Target Synonym:
EN 7;GX;HSPC 022;HSPC022;p21 Rac 2;RAC 2;Ras related C3 botulinum toxin substrate 2;Ras related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac2);Ras related C3 botulinum toxin substrate 3;Rho family small GTP binding protein Rac 2;Small G protein
UNIProt ID:
P15153