Purified Anti-Mouse/Human CD11b Antibody[M1/70]

Product Code: E-AB-F1081A

Code	Size	Price

E-AB-F1081A-25ug

25ug

£87.00

Quantity:

E-AB-F1081A-100ug

100ug

£111.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Rat

Antibody Isotype: Rat IgG2b, κ

Antibody Clone: M1/70

Regulatory Status: RUO

Target Species:

Human
Mouse

Application: Flow Cytometry

Shipping:

Ice packs

Storage:

Store at 2-8°C. Do not freeze.

Documents

Further Information

Abbreviation:

CD11b

Background:

CD11b is < 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Buffer:

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.

Concentration:

0.5 mg/mL

Conjugation:

Unconjugated

GeneID:

164,093,684

Target Synonym:

Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;

UNIProt ID:

P05555;P11215;

Usage:

Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 0.125 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

https://www.sciencedirect.com/science/article/pii/S1567576920338145

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