PTPRA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60533-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60533-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60533-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PTPRA
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200
Immunogen:
Recombinant fusion protein of human PTPRA (NP_543031.1).
Purification method:
Affinity purification
Target Synonym:
PTPRA;HEPTP;HLPR;HPTPA;HPTPalpha;LRP;PTPA;PTPRL2;R-PTP-alpha;RPTPA
UNIProt ID:
P18433