PSMC5 Polyclonal Antibody

Contact us
Elabscience
Product Code: E-AB-60331
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-60331-60uL60uL£210.00
Quantity:
E-AB-60331-120uL120uL£291.00
Quantity:
E-AB-60331-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of extracts of various cell lines using PSMC5 Polyclonal Antibody at dilution of 1:1000.
2 / 2
Immunofluorescence analysis of MCF-7 cells using PSMC5 Polyclonal Antibody
❮❯

Western blot analysis of extracts of various cell lines using PSMC5 Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of MCF-7 cells using PSMC5 Polyclonal Antibody

Documents

Further Information

Abbreviation:
PSMC5
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
44kDa/45kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PSMC5 (NP_002796.4).
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
PSMC5;S8;SUG-1;SUG1;TBP10;TRIP1;p45;p45/SUG;ATPase 5
UNIProt ID:
P62195