PRKCA Polyclonal Antibody
Code | Size | Price |
---|
E-AB-60056-60uL | 60uL | £210.00 |
Quantity:
E-AB-60056-120uL | 120uL | £291.00 |
Quantity:
E-AB-60056-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
PRKCA
Background:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
76kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
A synthetic peptide of human PRKCA
ObservedMW:
80KDa
Purification method:
Affinity purification
Target Synonym:
PRKCA;AAG6;PKC-alpha;PKCA;PRKACA;PKC alpha
UNIProt ID:
P17252