PPP2R4 Polyclonal Antibody

Elabscience
Product Code: E-AB-60498
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-60498-60uL60uL£210.00
Quantity:
E-AB-60498-120uL120uL£291.00
Quantity:
E-AB-60498-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of U2OS cells using Ser/thr-PP2A activator (PTPA) Polyclonal Antibody Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U2OS cells using Ser/thr-PP2A activator (PTPA) Polyclonal Antibody Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
PPP2R4
Background:
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
31kDa/33kDa/36kDa/40kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PPP2R4
Purification method:
Affinity purification
Target Synonym:
PTPA;PP2A;PPP2R4;PR53
UNIProt ID:
Q15257