PPL Polyclonal Antibody

Elabscience
Product Code: E-AB-61425
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-61425-60uL60uL£210.00
Quantity:
E-AB-61425-120uL120uL£291.00
Quantity:
E-AB-61425-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of MCF7 cells using PPL Polyclonal Antibody

Immunofluorescence analysis of MCF7 cells using PPL Polyclonal Antibody

Documents

Further Information

Abbreviation:
PPL
Background:
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human PPL (NP_002696.3).
Purification method:
Affinity purification
Target Synonym:
PPL
UNIProt ID:
O60437