PIDD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-63806-60uL | 60uL | £210.00 |
Quantity:
| E-AB-63806-120uL | 120uL | £291.00 |
Quantity:
| E-AB-63806-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PIDD
Background:
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
33kDa/37kDa/58kDa/66kDa/82kDa/97kDa/99kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human PIDD (NP_665893.2).
ObservedMW:
100-110kDa
Purification method:
Affinity purification
Target Synonym:
PIDD1;LRDD;PIDD
UNIProt ID:
Q9HB75