PGR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70121-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70121-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70121-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PGR
Background:
PGR,also named as NR3C3 and PR,belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1.32 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor
Purification method:
Affinity purification
Target Synonym:
NR3C3;Nuclear receptor subfamily 3 group C member 3;PGR;PR;PRA;PRB;PRGR;Progesterone receptor;Progestin receptor form A;Progestin receptor form B
UNIProt ID:
P06401,Q00175,Q63449