PERK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70363-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70363-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70363-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PERK
Background:
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:400-1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Human PERK
Purification method:
Affinity purification
Target Synonym:
DKFZp781H1925;E2AK3;EC 2.7.11.1;Eif2ak3;Eukaryotic translation initiation factor 2 alpha kinase 3;Eukaryotic translation initiation factor 2-alpha kinase 3;Heme regulated EIF2 alpha kinase;HRI;HsPEK;Pancreatic eIF2 alpha kinase;Pancreatic eIF2-alpha kinase;PEK;PRKR like endoplasmic reticulum kinase;PRKR-like endoplasmic reticulum kinase;WRS
UNIProt ID:
Q9NZJ5