PDE1B Polyclonal Antibody

Elabscience
Product Code: E-AB-60606
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-60606-60uL60uL£210.00
Quantity:
E-AB-60606-120uL120uL£291.00
Quantity:
E-AB-60606-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of extracts of various cell lines using PDE1B Polyclonal Antibody at 1:500 dilution.
2 / 2
Immunohistochemistry of paraffin-embedded rat brain using PDE1B Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Western blot analysis of extracts of various cell lines using PDE1B Polyclonal Antibody at 1:500 dilution.
Immunohistochemistry of paraffin-embedded rat brain using PDE1B Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Documents

Further Information

Abbreviation:
PDE1B
Background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
59kDa/61kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human PDE1B
ObservedMW:
59kDa
Purification method:
Affinity purification
Target Synonym:
PDE1B;HEL-S-79p;PDE1B1;PDES1B
UNIProt ID:
Q01064