PCK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40269-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40269-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40269-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40269-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PCK1
Background:
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200
Immunogen:
Recombinant Rat Phosphoenolpyruvate carboxykinase, cytosolic [GTP] protein
Purification method:
Antigen Affinity Purification
Target Synonym:
cytosolic [GTP];GTP;PCK1;PCKGC;PEP carboxykinase;PEPCK-C;PEPCK1;PEPCKC;Phosphoenolpyruvate carboxykinase 1 (soluble);Phosphoenolpyruvate carboxykinase 1;Phosphoenolpyruvate carboxykinase;Phosphoenolpyruvate carboxykinase;cytosolic [GTP];Phosphoenolpyruvate carboxykinase;cytosolic;Phosphoenolpyruvate carboxylase;Phosphopyruvate carboxylase
UNIProt ID:
P07379