P2RX7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-63428-60uL | 60uL | £210.00 |
Quantity:
| E-AB-63428-120uL | 120uL | £291.00 |
Quantity:
| E-AB-63428-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
P2RX7
Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
14kDa/31kDa/35kDa/41kDa/49kDa/58kDa/68kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant fusion protein of human P2RX7
ObservedMW:
75KDa
Purification method:
Affinity purification
Target Synonym:
P2RX7;P2X7
UNIProt ID:
Q99572