NTRK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70155-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70155-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70155-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NTRK2
Background:
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
92kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein corresponding to Mouse TRKB
ObservedMW:
90/140kDa
Purification method:
Affinity purification
Target Synonym:
AI848316;BDNF tropomyosine receptor kinase B;BDNF/NT 3 growth factors receptor;BDNF/NT-3 growth factors receptor;Brain derived neurotrophic factor receptor;C030027L06Rik;EC 2.7.10.1;GP145 TrkB;GP145-TrkB;GP145-TrkB/GP95-TrkB;GP95 TrkB;Neurotrophic receptor tyrosine kinase 2;Neurotrophic tyrosine kinase receptor type 2;Neurotrophin receptor tyrosine kinase type 2;NTRK 2;Ntrk2;NTRK2;Obesity;hyperphagia;and developmental delay;included;RATTRKB1;Tkrb;Trk B;Trk-B;TRKB;TrkB tyrosine kinase;TRKB1;Tropomyosin related kinase B;tyrosine kinase receptor B;Tyrosine receptor kinase B
UNIProt ID:
Q16620,P15209,Q63604
References
- https://link.springer.com/article/10.1007/s12035-022-03026-8