NQO1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70139-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70139-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70139-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NQO1
Background:
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
31kDa
Concentration:
350 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse NQO1
ObservedMW:
31kDa
Purification method:
Affinity purification
Target Synonym:
Azoreductase;Cytochrome b 5 reductase;DHQU;DIA 4;DIA4;Diaphorase (NADH/NADPH) (cytochrome b 5 reductase);Diaphorase (NADH/NADPH);Diaphorase 4;Dioxin inducible 1;DT diaphorase;DT-diaphorase;DTD;Menadione reductase;NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase quinone 1;NAD(P)H menadione oxidoreductase 1 dioxin inducible;NAD(P)H quinone dehydrogenase 1;NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NMOR 1;NMOR I;NMOR1;NMORI;NQO 1;NQO1;NQO1;Phylloquinone reductase;QR 1;QR1;Quinone reductase 1
UNIProt ID:
P15559,P05982,Q64669